MMI CellDetector automated target recognition software: identify targets on the instrument, then cut or aspirate. Authorized distributor in China: Oriental Horizon Technology Co Ltd (Beijing).

Introduction

CellDetector is the automated target recognition software from MMI (Germany). It locates target cells and target regions automatically in whole-slide or live microscope images acquired on the same instrument. The recognition results can be passed directly to CellCut laser microdissection, CellEctor single-cell isolation, and the downstream retrieval steps that follow CellScan multimodal panoramic scanning on the same instrument. The software is particularly suited to spatial multi-omics experiments in which targets are cut or aspirated after recognition.

Figure. CellDetector automated target recognition in MMI workflows.

Functions

• Recognizes targets automatically from image features such as color, morphology, and relative size, which reduces the effort of outlining targets one by one.

• Connects to MMI CellTools and to workflows on the same instrument, so that recognition results proceed directly to cutting or aspiration.

• Supplied as optional software that can be combined with CellCut, CellEctor, and CellScan according to the needs of each project.

• The functions of CellDetector and of the ShapeImport data import software are distinct: CellDetector performs automated recognition on the instrument, whereas ShapeImport is used when third-party contours or annotations are imported before cutting.

Use with cutting, isolation and scanning workflows

• With CellScan: after whole-slide scanning, targets are recognized automatically on the panoramic image and then cut by CellCut on the same instrument.

• With CellCut: target regions or target cells are located automatically before cutting, which shortens the time needed to prepare outlines.

• With CellEctor: an optional recognize-then-aspirate workflow locates targets under the microscope, after which the capillary performs isolation and deposition.

• The default optical platform is an inverted research microscope (for example, Nikon Ti2-E, EVIDENT IX83 / IX85, or ZEISS Axio Observer 7). The software can also be added to budget configurations and is not tied to a particular host microscope tier.

Typical applications

Retrieval of target regions from tissue sections in spatial multi-omics studies, microscopic localization and downstream sampling of rare cells or cells with a defined phenotype, and research laboratories that require a continuous scan, recognize, and cut or aspirate workflow on one instrument.

For research use only.